Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity.
نویسندگان
چکیده
We report on a novel strategy to improve microfluidic immunoassay sensitivity by introducing chemiluminescence resonance energy transfer (CRET) into the immunoreactions. The proposed CRET-based immunoassay for estradiol (E2, as a model analyte) is one of the most sensitive immunoassay with a limit of detection at 3.6 × 10(-11) M E2 in a microfluidic format.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 5 شماره
صفحات -
تاریخ انتشار 2012